Anti-AGTR2 antibody produced in rabbit
SIGMA/SAB3500098 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-AT2; Anti-AT2R; Anti-Angiotensin II receptor type 2; Anti-MRX88
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of AGTR2 in rat liver tissue with AGTR2 antibody at 5 μg/mL.
Immunoblotting Anti-AGTR2: Cat. No. SAB3500098: AGTR2 in mouse liver tissue lysate with AGTR2 antibody at 0.5 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | predicted mol wt 40 kDa |
| NCBI accession no. | AAS45437   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | rat, mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | P50052 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
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| General description: | Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction. |
| Immunogen: | AGTR2 antibody was raised against a 16 amino acid peptide from near the center of human AGTR2. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3500098 . |
| Physical form: | Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |