Anti-TRESK antibody produced in rabbit
SIGMA/SAB3500141 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-KCNK18; Anti-Potassium channel subfamily K member 18; Anti-TRESK2; Anti-TRIK
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of TRESK in rat brain tissue with TRESK antibody at 5 μg/mL.
Immunofluorescence Immunofluorescence of TRESK in Rat Brain cells with TRESK antibody at 20 μg/mL.
Immunoblotting Anti-TRESK: Cat. No. SAB3500141: Western blot analysis of TRESK in rat brain tissue lysate with TRESK antibody at (A) 1 and (B) 2 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NP_862823   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human, rat, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| immunohistochemistry: suitable | |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | Q7Z418 |
| Biochem/physiol Actions: | Potassium two pore domain channel subfamily K member 18 (KCNK18) or TRESK contributes to background K+ currents in sensory neurons. Mutations in the gene encoding it have been associated with familial migraine with aura. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
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| General description: | Potassium two pore domain channel subfamily K member 18 (KCNK18) or TRESK is part of the potassium channel family. It is expressed in trigeminal and dorsal root ganglions. The protein is activated by calcium signals. The TRESK gene is localized on human chromosome 10q25.3. |
| Immunogen: | TRESK antibody was raised against a 17 amino acid peptide from near the center of human TRESK. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3500141 . |
| Physical form: | Supplied in PBS with 0.02% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |