Anti-LXR-A antibody produced in rabbit
SIGMA/SAB3500178 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-LXRA; Anti-Liver X receptor A; Anti-NR1H3; Anti-Nuclear receptor subfamily 1 group H member 3
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of LXR-A in rat liver tissue with LXR-A antibody at 5 μg/mL.
Immunofluorescence Immunofluorescence of LXR-A in rat liver tissue with LXR-A antibody at 20 μg/mL.
Immunoblotting Anti-LXR-A: Cat. No. SAB3500178: Western blot analysis of LXR-A in rat liver tissue lysate with LXR-A antibody at (A) 1 and (B) 2 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | predicted mol wt 44-49 kDa |
| NCBI accession no. | NP_005684   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | rat, human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| immunohistochemistry: suitable | |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | Q13133 |
| Biochem/physiol Actions: | The gene LXR α (liver X receptor α) encodes a protein that plays an important role in the control of cholesterol homeostasis. LXRs have been found to regulate inflammatory response in macrophages. They are also involved in the regulation of cell proliferation. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | The gene LXR α (liver X receptor α) is a member of LXRs that belong to the nuclear receptor superfamily. The encoded protein is expressed predominantly in macrophages, liver, intestine, kidney, lung and adipose tissue. The gene is mapped to human chromosome 11p11.2. The protein contains a DNA-binding domain that requires the ligand-binding domain to heterodimerize with a retinoid X receptor partner for its DNA-binding activity. |
| Immunogen: | LXR-A antibody was raised against a 15 amino acid peptide from near the amino terminus human LXR-A. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3500178 . |
| Physical form: | Supplied in PBS with 0.02% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |