Anti-Slc22A17 antibody produced in rabbit
SIGMA/SAB3500306 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-BOCT; Anti-BOIT; Anti-Brain-type organic cation transporter; Anti-Solute carrier family 22 member 17
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of SLC22A17 in mouse kidney tissue with SLC22A17 antibody at 2.5 μg/mL.
Immunofluorescence Anti-Slc22A17: Cat. No. SAB3500306: Immunofluorescence of Slc22A17 in rat kidney tissue cells with Slc22A17 antibody at 20 μg/mL.
Western Blotting Anti-Slc22A17: Western blot analysis of Slc22A17 in SK-N-SH lysate with Slc22A17 antibody at 0.5 μg/mL in (A) the presence and (B) the absence of blocking peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | predicted mol wt 59 kDa |
| NCBI accession no. | Q8WUG5   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | rat, human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| indirect ELISA: suitable | |
| indirect immunofluorescence: suitable | |
| western blot: suitable | |
| UniProt accession no. | Q8WUG5 |
| Biochem/physiol Actions: | Slc22A17 expression is associated with important biological processes such as cell differentiation, apoptosis and inflammation. Slc22A17 mediates endocytosis of neutrophil gelatinase-associated lipocalin, a mammalian protein that can bind to bacterial siderophore enterobactin with high affinity. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
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| General description: | Slc22A17 gene is also referred to as brain organic cation transporter (BOCT) and is mapped to human chromosome 14q11.2. The encoded protein is predominantly localized to kidney and liver. The Slc22 proteins consists of 12 transmembrane (TM) α-helices with an extended loop (extracellular) between the first and the second transmembrane regions, and a loop (intracellular) between the sixth and the seventh transmembrane regions. |
| Immunogen: | Slc22A17 antibody was raised against a 14 amino acid peptide near the carboxy terminus of the human Slc22A17. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3500306 . |
| Physical form: | Supplied in PBS with 0.02% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |