Anti-IL-23 antibody produced in rabbit
SIGMA/SAB3500310 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-IL-27 p28; Anti-Interleukin-27
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of IL-23 in human pancreas tissue with IL-23 antibody at 5 μg/mL.
Immunocytochemistry Anti-IL-23: Cat. No. SAB3500310: Immunocytochemistry of IL-23 in Raji cells with IL-23 antibody at 10 μg/mL.
Immunofluorescence Immunofluorescence of IL-23 in Raji cells with IL-23 antibody at 20 μg/mL.
Immunoblotting Anti-IL-23: Cat. No. SAB3500310: Western blot analysis of IL-23 in Raji lysate with IL-23 antibody at 1 μg/mL in the (A) absence and (B) presence of blocking peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | predicted mol wt 21 kDa |
| NCBI accession no. | AAH66268   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunocytochemistry: suitable |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | Q9NPF7 |
| Application: | Anti-IL-23 antibody has been used in western blotting. |
| Biochem/physiol Actions: | The IL-23 plays a major role in cutaneous immune-mediated inflammatory diseases like psoriasis, allergic contact dermatitis and atopic dermatitis. It is involved in cellular immunity driving the expansion, stabilization and survival of Th17 cells. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | IL-23 is a pro-inflammatory cytokine. It is mostly synthesized by activated DC (dendritic cells) and macrophages. It is a 20.7 kDa protein that has 189 amino acids. IL-23 is mostly expressed on activated/memory T cells and natural killer (NK) cells. This gene is located on human chromosome 12q13.3. |
| Immunogen: | IL-23 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human IL-23. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3500310 . |
| Physical form: | Supplied in PBS with 0.02% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |