Anti-TMEM16A antibody produced in rabbit
SIGMA/SAB3500318 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-Ano1; Anti-Anoctamin 1; Anti-Calcium activated chloride channel; Anti-DOG1; Anti-TAOS1
Product Type: Chemical
Immunoblotting Anti-TMEM16A: Cat. No. SAB3500318: Western blot analysis of TMEM16A in A549 cell lysate with TMEM16A antibody at 1 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NP_060513   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: suitable | |
| UniProt accession no. | Q5XXA6 |
| Biochem/physiol Actions: | Transmembrane member 16A (TMEM16A) or Ano1 is crucial for normal electrical slow waves and for the proliferation of interstitial cells of Cajal (ICC). The protein has a role in smooth muscle contraction, salivary secretion and cardiac and neuronal excitability. TMEM16A has been associated with head and neck squamous cell carcinoma and breast cancer. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Transmembrane member 16A (TMEM16A) or Anoctamin1 (Ano1) is a calcium-activated chloride channel. It is expressed in the interstitial cells of Cajal (ICC) in the gastrointestinal tract. The gene encoding this protein is localized on human chromosome 11q13.3. |
| Immunogen: | TMEM16A antibody was raised against a 17 amino acid peptide from near the amino terminus of human TMEM16A. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3500318 . |
| Physical form: | Supplied in PBS with 0.02% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |