Anti-CLDN1 antibody produced in rabbit
SIGMA/SAB3500438 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-CLD1; Anti-CLDN1; Anti-Claudin 1; Anti-ILVASC; Anti-SEMP1
MDL Number: MFCD02096101
Product Type: Chemical
Immunocytochemistry Anti-CLDN1: Cat. No. SAB3500438: Immunocytochemistry of CLDN1 in HepG2 cells with CLDN1 antibody at 5 μg/mL.
Immunofluorescence Immunofluorescence of CLDN1 in HepG2 cells with CLDN1 antibody at 20 μg/mL.
Immunoblotting Anti-CLDN1: Cat. No. SAB3500438: Western blot analysis of CLDN1 in HepG2 cell lysate with CLDN1 antibody at (A) 1 and (B) 2 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | CAG33419   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | rat, mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunocytochemistry: suitable |
| immunofluorescence: suitable | |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | O95832 |
| Biochem/physiol Actions: | Claudin 1 (CLDN1) has a role in epithelial-mesenchymal transition. It is a sealing and tightening junctional protein. CLDN1 has been shown to be downregulated in lung adenocarcinoma. Mutations in this gene have also been linked to neonatal ichthyosis and sclerosing cholangitis. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Claudin 1 (CLDN1) is a component of tight junctions. It is part of the transmembrane tight junction protein family. The CLDN1 gene is localized on human chromosome 3q28. |
| Immunogen: | CLDN1 antibody was raised against a 20 amino acid peptide near the carboxyl terminus of human CLDN1. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3500438 . |
| Physical form: | Supplied in PBS with 0.02% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |