Anti-CD81 antibody produced in rabbit
SIGMA/SAB3500454 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-S5.7; Anti-TAPA1; Anti-TSPAN28
MDL Number: MFCD01633235
Product Type: Chemical
Immunohistochemistry Anti-CD81: Cat. No. SAB3500454: Immunohistochemistry of CD81 in human lung tissue with CD81 antibody at 5 μg/mL.
Immunofluorescence Immunofluorescence of CD81 in A549 cells with CD81 antibody at 20 μg/mL.
Immunoblotting Anti-CD81: Cat. No. SAB3500454: Western blot analysis of CD81 in human lung tissue lysate with CD81 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking petide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | predicted mol wt 26 kDa |
| NCBI accession no. | NP_004347   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | rat, human, mouse |
| species reactivity (predicted by homology) | bovine |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: suitable |
| immunofluorescence: suitable | |
| immunohistochemistry: suitable | |
| western blot: suitable | |
| UniProt accession no. | P60033 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | CD81 Antibody: CD81 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family, a group of cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD81 is a cell surface glycoprotein that associates with integrins and appears to promote muscle cell fusion and support myotube maintenance. Along with SCARB1, LDL-R, and CLDN1, CD81 has been reported to be an entry factor for the Hepatitis C virus. Finally, recent evidence indicates that the CD81 gene is localized in a tumor-suppressor gene region and is thus a candidate gene for malignancies. |
| Immunogen: | CD81 antibody was raised against a 20 amino acid peptide near the amino terminus of human CD81. The immunogen is located within amino acids 30 - 80 of CD81. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3500454 . |
| Physical form: | Supplied in PBS with 0.02% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |