Anti-ZEB1 antibody produced in rabbit
SIGMA/SAB3500514 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-AREB6; Anti-BZP; Anti-TCF8; Anti-Zinc finger E-box binding homeobox 1
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of ZEB1 in human liver tissue with ZEB1 antibody at 5 μg/mL.
Immunocytochemistry Anti-ZEB1: Cat. No. SAB3500514: ZEB1 in HeLa cells with ZEB1 antibody at 20 μg/mL.
Immunocytochemistry Immunocytochemistry of ZEB1 in HeLa cells with ZEB1 antibody at 20 μg/mL.
Immunofluorescence Immunofluorescence of ZEB1 in HeLa cells with ZEB1 antibody at 20 μg/mL.
Immunoblotting Anti-ZEB1: Cat. No. SAB3500514: ZEB1 in HeLa cell lysate with ZEB1 antibody at 1 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | predicted mol wt 124 kDa |
| NCBI accession no. | CAI12550   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunocytochemistry: suitable |
| immunofluorescence: suitable | |
| immunohistochemistry: suitable | |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | P37275 |
| Application: | Anti-ZEB1 antibody produced in rabbit has been used in western blotting. |
| Biochem/physiol Actions: | Zinc finger E-box-binding homeobox 1 (ZEB1) controls the expression of E-cadherin as a repressor. It plays an important role in tumor invasion and metastasis. Epigenetic suppression of ZEB1 might be a useful tool for overcoming drug resistance in human breast cancer. Mutations in this gene are associated with posterior polymorphous corneal dystrophy and Fuchs′ endothelial corneal dystrophy (FECD6). |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Zinc finger E-box-binding homeobox 1 (ZEB1) is an EMT (epithelial-mesenchymal transition) transcription factor. The gene encoding this protein is localized on human chromosome 10p11.2. |
| Immunogen: | ZEB1 antibody was raised against a 15 amino acid peptide near the center of human ZEB1. The immunogen is located within amino acids 530 - 580 of ZEB1. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3500514 . |
| Physical form: | Supplied in PBS with 0.02% sodium azide. |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |