Anti-MFSD2A antibody produced in rabbit
SIGMA/SAB3500576 - affinity isolated antibody, buffered aqueous solution
Synonym: Mfsd2A Antibody; Mfsd2A Antibody - Anti-MFSD2A antibody produced in rabbit; Anti-Major facilitator superfamily domain-containing protein 2A; Anti-mfsd2aa
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of MFSD2A in mouse lung tissue with MFSD2A antibody at 2.5 μg/mL.
Immunofluorescence Immunofluorescence of MFSD2A in Rat Lung cells with MFSD2A antibody at 20 μg/mL.
Immunoblotting Anti-MFSD2A: Cat. No. SAB3500576: MFSD2A in rat lung tissue lysate with MFSD2A antibody at (A) 1 and (B) 2 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NP_001007452   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | mouse, rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| immunohistochemistry: suitable | |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | Q5U3U7 |
| Biochem/physiol Actions: | Major facilitator superfamily domain containing 2a (Mfsd2a) acts as a transporter for the essential omega-3 fatty acid docosahexaenoic acid. It is essential at the blood-brain barrier for postnatal brain growth. A leaky blood-brain barrier from embryonic stages through to adulthood is observed if there is a genetic variation in this gene. Mutation in MFSD2A gene results in microcephaly and ventriculomegaly. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Major facilitator superfamily domain containing 2a (Mfsd2a)is a sodium-dependent lysophosphatidylcholine (LPC) transporter. The endothelium of the micro vessels in blood brain barrier express high levels of Mfsd2a. |
| Immunogen: | MFSD2A antibody was raised against an 18 amino acid peptide near the carboxy terminus of human MFSD2A. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3500576 . |
| Physical form: | Supplied in PBS with 0.02% sodium azide. |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |