Anti-ZIP8 antibody produced in rabbit
SIGMA/SAB3500598 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-BIGM103; Anti-PP3105; Anti-SLC39A8; Anti-Slc39A8; Anti-Solute carrier family 39 member A8
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of ZIP8 in human spleen tissue with ZIP8 antibody at 5 μg/mL.
Immunofluorescence Immunofluorescence of ZIP8 in human spleen tissue with ZIP8 antibody at 20 μg/mL.
Immunoblotting Anti-ZIP8: Cat. No. SAB3500598: ZIP8 in human spleen tissue lysate with ZIP8 antibody at (A) 1 and (B) 2 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NP_071437   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| immunohistochemistry: suitable | |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | Q9C0K1 |
| Application: | Anti-ZIP8 antibody produced in rabbit has been used in immunocytochemistry. |
| Biochem/physiol Actions: | Solute carrier family 39 member 8 (SLC39A8) co-transports divalent metal cations like cadmium, zinc, manganese and iron. It has a crucial role in the cellular uptake of cadmium. The protein is a target of nuclear-factor κB (NF-κB) and has a role in pro-inflammatory responses. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
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| General description: | Solute carrier family 39 member 8 (SLC39A8), also known as zinc- and iron-related protein 8 (ZIP8), is a plasma membrane transporter protein. It is part of the solute carrier gene superfamily. The gene encoding SLC39A8 is localized on human chromosome 4q24. |
| Immunogen: | ZIP8 antibody was raised against a 18 amino acid peptide near the carboxy terminus of human ZIP8. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3500598 . |
| Physical form: | Supplied in PBS with 0.02% sodium azide. |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |