Anti-TET2 antibody produced in rabbit
SIGMA/SAB3500711 - affinity isolated antibody
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of TET2 in human colon carcinoma tissue with TET2 antibody at 2 μg/mL.
Immunofluorescence Immunofluorescence of TET2 in human colon carcinoma tissue with TET2 antibody at 20 μg/mL.
Immunoblotting Anti-TET2; Cat. No. SAB3500711; Western blot analysis of TET2 in SK-N-SH cell lysate with TET2 antibody at 1 μ/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| mol wt | 220 kDa |
| NCBI accession no. | NP_001120680   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: suitable |
| western blot: suitable | |
| UniProt accession no. | Q6N021 |
| Application: | Anti-TET2 antibody produced in rabbit has been used in Western blotting. |
| Biochem/physiol Actions: | Tet methylcytosine dioxygenase 2 (TET2) is involved in the conversion of 5-methylcytosine to 5-hydroxymethyl-cytosine (5hmC). It also has a role in stimulating DNA demethylation and lymphomagenesis. Mutations in the gene encoding TET2 have been linked to myelodysplastic syndromes. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
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| General description: | Tet methylcytosine dioxygenase 2 (TET2) is part of the Fe(II)/α-ketoglutarate-de |
| Immunogen: | Antibody was raised against an 18 amino acid peptide near the amino terminus of human TET2. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3500711 . |
| Physical form: | Supplied at 1 mg/mL in PBS with 0.02% sodium azide. |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |