Anti-Periostin antibody,Mouse monoclonal
SIGMA/SAB4200197 - clone 47, purified from hybridoma cell culture
Synonym: Periostin Antibody; Periostin Antibody - Monoclonal Anti-Periostin antibody produced in mouse; Anti-OSF2; Anti-Osteoblast specific factor 2; Anti-PDLPOSTN; Anti-POSTN
Product Type: Chemical
Immunoblotting Whole extract of HEK-293T cells overexpressing human Periostin was separated on SDS-PAGE and probed with Monoclonal Anti-Periostin Clone: 47 (Cat. No. SAB4200197). The antibody was developed using Goat Anti-Mouse IgG-Peroxidase (Cat. No. A2304) and a chemiluminescent substrate. Lanes 1. 4 μg/mL antibody 2. 2 μg/mL antibody 3. 1 μg/mL antibody
| antibody form | purified from hybridoma cell culture |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 47, monoclonal |
| concentration | ~1.0 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgG1 |
| mol wt | antigen ~88 kDa |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 2-4 μg/mL using whole extracts of HEK-293T cells over expressing human Periostin |
| UniProt accession no. | Q15063   |
| Application: | Monoclonal Anti-Periostin antibody produced in mouse has been used to develop a periostin imaging PET probe. |
| Biochem/physiol Actions: | Periostin (POSTN) has a role in the differentiation and cell adhesion of osteogenic cells. It functions as a biomarker of T-helper cells type 2-mediated inflammatory diseases. The protein has been associated with various cancers. POSTN is involved in epithelial-mesenchymal transition and extracellular matrix degradation. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Periostin (POSTN) is also known as osteoblast-specific factor-2. It is a 90 kDa protein expressed in the extracellular matrix and bones. POSTN is an adhesive glycoprotein. The gene encoding this protein is localized on human chromosome 13q13.3. |
| Immunogen: | human Periostin recombinant protein. The human protein shares 87% homology with the mouse protein. |
| Physical form: | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide. |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |