Anti-Digoxin antibody, Mouse monoclonal
SIGMA/SAB4200669 - clone DI-22, purified from hybridoma cell culture
Synonym: 12β-Hydroxydigitoxin; Monoclonal Anti-Digoxin antibody produced in mouse
Product Type: Chemical
ELISA Monoclonal Anti-Digoxin, Clone: DI-22 (Cat. No. SAB4200669) was serially diluted to detect Digoxin by indirect ELISA.
| antibody form | purified from hybridoma cell culture |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | DI-22, monoclonal |
| concentration | 1.0 mg/mL |
| ~1 mg/mL | |
| isotype | IgG1 |
| Quality Level | 200  |
| shipped in | dry ice |
| species reactivity | human, mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 0.15-0.3 μg/mL |
| Application: | Monoclonal Anti-Digoxin antibody produced in mouse has been used in: • enzyme linked immunosorbent assay (ELISA) • dot blot • flow cytometry • immunofluorescence • DNA hybridization • in-situ hybridization (ISH) |
| Biochem/physiol Actions: | Digoxin is an uncharged glycoside which is given to humans with congestive heart failure. It enhances the force of myocardial contraction. Anti-digoxin antibodies can be used to reverse the effects of digoxin. |
| Biochem/physiol Actions: | Unlike other oral inotrope, digoxin does not promote mortality. It inhibits sodium potassium ATPase membrane pump. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Monoclonal Anti-Digoxin (mouse IgG1 isotype) is derived from the hybridoma DI-22 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with digoxin conjugated to keyhole limpet hemocyanin (KLH). |
| Immunogen: | immunized with Digoxin |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |