Anti-Elastin antibody, Mouse monoclonal
SIGMA/SAB4200718 - clone BA-4, purified from hybridoma cell culture
Synonym: Anti-ELN; Anti-Tropoelastin
Product Type: Chemical
Immunohistochemistry Staining of formalin-fixed, paraffin-embedded Sheep artery sections with 20 μg/mL Anti-Elastin antibody, Mouse monoclonal, Clone: BA-4 (Cat. No. SAB4200718) using biotin/ExtrAvidin®-Peroxidase.
| antibody form | purified from hybridoma cell culture |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | BA-4, monoclonal |
| concentration | ~1.0 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgG1 |
| Quality Level | 200  |
| shipped in | dry ice |
| species reactivity | sheep, hamster, bovine, goat, frog, rabbit, porcine, human, guinea pig, canine |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoblotting: suitable |
| immunohistochemistry: 10-20 μg/mL using enzyme-retrieved formalin-fixed, paraffin-embedded sheep arterial tissue sections | |
| immunoprecipitation (IP): suitable | |
| UniProt accession no. | P15502  |
| Application: | Anti-Elastin antibody, Mouse monoclonal has been used in: • immunohistochemistry • immunoblot • immunoprecipitation |
| Biochem/physiol Actions: | Elastin (ELN) provides elasticity and is integrated with other proteins from the ECM in elastic fibrils. Elastin undergoes changes of morphology with aging and at many disease states. In addition, several heritable diseases, such as supravalvular aortic stenosis, cutis laxa, Marfan syndrome, pseudoxanthoma elasticum and Buschke-Ollendorf syndrome, may result from molecular defects of elastin. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Anti-Elastin antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the BA-4 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with bovine alpha-Elastin. |
| Immunogen: | bovine alpha-Elastin |
| Physical form: | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |