Anti-phospho-ELK1 (pSer383) antibody produced in rabbit
SIGMA/SAB4300003 - affinity isolated antibody
Synonym: Anti-ELK1, member of ETS oncogene family antibody produced in rabbit
MDL Number: MFCD01092332
Product Type: Chemical
Immunohistochemistry Anti-phospho-ELK1 (pSer383): SAB4300003: Analysis of paraffin-embedded human breast carcinoma tissue using Anti-phospho-ELK1 (pSer383) antibody (left) or the same antibody preincubated with blocking peptide (right).
Immunoblotting Anti-phospho-ELK1 (pSer383): SAB4300003: Analysis of extracts from HT29 cells untreated or treated with UV using Anti-phospho-ELK1 (pSer383) antibody.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (T-L-SP-P-I) |
| isotype | IgG |
| mol wt | ~47 kDa |
| NCBI accession no. | NP_001107595.1   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human, rat |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer383) |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P19419 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Elk-1 is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Alternatively spliced transcript variants encoding the same protein have been found for this gene. |
| Immunogen: | Peptide sequence around phosphorylation site of serine 383 (T-L-S(p)-P-I), according to the protein ELK1. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |