Anti-phospho-ERBB2 (pTyr1248) antibody produced in rabbit
SIGMA/SAB4300061 - affinity isolated antibody
Synonym: Anti-CD340 antibody produced in rabbit; Anti-HER-2 antibody produced in rabbit; Anti-HER-2/neu antibody produced in rabbit; Anti-HER2 antibody produced in rabbit; Anti-v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro / glioblastoma derived oncogene homolog (avian) antibody produced in rabbit
MDL Number: MFCD06798486
Product Type: Chemical
Immunohistochemistry Anti-phospho-ERBB2 (pTyr1248): SAB4300061: Analysis of paraffin-embedded human breast carcinoma tissue using Anti-phospho-ERBB2 (pTyr1248) antibody (left) or the same antibody preincubated with blocking peptide (right).
Immunofluorescence Anti-phospho-ERBB2 (pTyr1248): SAB4300061: Staining of methanol-fixed MCF7 cells using Anti-phospho-ERBB2 (pTyr1248) antibody (Red).
Immunoblotting Anti-phospho-ERBB2 (pTyr1248): SAB4300061: Analysis of extracts from MDA cells untreated or treated with EGF using Anti-phospho-ERBB2 (pTyr1248) antibody.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (P-E-YP-L-G) |
| isotype | IgG |
| mol wt | ~185 kDa |
| NCBI accession no. | NP_001005862.1   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, mouse, human |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pTyr1248) |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 |
| indirect immunofluorescence: 1:100-1:200 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P04626 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-alpha and amphiregulin. |
| Immunogen: | Peptide sequence around phosphorylation site of tyrosine1248 (P-E-Y(p)-L-G), according to the protein ERBB2. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |