Anti-phospho-G3BP1 (pSer232) antibody produced in rabbit
SIGMA/SAB4300064 - affinity isolated antibody
Synonym: Anti-G3BP antibody produced in rabbit; Anti-GTPase activating protein (SH3 domain) binding protein 1 antibody produced in rabbit; Anti-HDH-VIII antibody produced in rabbit; Anti-MGC111040 antibody produced in rabbit
MDL Number: MFCD02262927
Product Type: Chemical
Immunohistochemistry Anti-phospho-G3BP1 (pSer232): SAB4300064: Analysis of paraffin-embedded human breast carcinoma tissue using Anti-phospho-G3BP1 (pSer232) antibody (left) or the same antibody preincubated with blocking peptide (right).
Immunofluorescence Anti-phospho-G3BP1 (pSer232): SAB4300064: Staining of methanol-fixed HeLa cells using Anti-phospho-G3BP1 (pSer232) antibody (Red).
Immunoblotting Anti-phospho-G3BP1 (pSer232): SAB4300064: Analysis of extracts from 293 cells untreated or treated with starvation using Anti-phospho-G3BP1 (pSer232) antibody.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (S-S-SP-P-A) |
| isotype | IgG |
| mol wt | ~60 kDa |
| NCBI accession no. | NP_005745.1   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer232) |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 |
| indirect immunofluorescence: 1:100-1:200 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | Q13283 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
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| General description: | May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA. |
| Immunogen: | Peptide sequence around phosphorylation site of serine 232 (S-S-S(p)-P-A), according to the protein G3BP1. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |