Anti-phospho-ICAM1 (pTyr512) antibody produced in rabbit
SIGMA/SAB4300065 - affinity isolated antibody
Synonym: Anti-BB2 antibody produced in rabbit; Anti-CD54 antibody produced in rabbit; Anti-P3.58 antibody produced in rabbit; Anti-intercellular adhesion molecule 1 antibody produced in rabbit
MDL Number: MFCD00240668
Product Type: Chemical
Immunoblotting Anti-phospho-ICAM1 (pTyr512): SAB4300065: Analysis of extracts from HUVEC cells using Anti-phospho-ICAM1 (pTyr512) antibody (Lane 2) and the same antibody preincubated with blocking peptide (Lane1).
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (K-K-YP-R-L) |
| isotype | IgG |
| mol wt | ~92 kDa |
| NCBI accession no. | NP_000192.2   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pTyr512) |
| technique(s) | western blot: 1:500-1:1000 |
| UniProt accession no. | P05362 |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
| Immunogen: | Peptide sequence around phosphorylation site of tyrosine 512 (K-K-Y(p)-R-L)., according to the protein ICAM1. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |