Anti-phospho-TP53 (pThr18) antibody produced in rabbit
SIGMA/SAB4300074 - affinity isolated antibody
Synonym: Anti-FLJ92943 antibody produced in rabbit; Anti-LFS1 antibody produced in rabbit; Anti-TRP53 antibody produced in rabbit; Anti-p53 antibody produced in rabbit; Anti-tumor protein p53 antibody produced in rabbit
MDL Number: MFCD00164709
Product Type: Chemical
Immunoblotting Anti-phospho-TP53 (pThr18): SAB4300074: Analysis of extracts from HT29 and MDA cells untreated or treated with anisomycin using Anti-phospho-TP53 (pThr18) antibody.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (Q-E-TP-F-S) |
| isotype | IgG |
| mol wt | ~53 kDa |
| NCBI accession no. | NP_000537.3   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pThr18) |
| technique(s) | western blot: 1:500-1:1000 |
| UniProt accession no. | P04637 |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. |
| Immunogen: | Peptide sequence around phosphorylation site of threonine 18 (Q-E-T(p)-F-S), according to the protein TP53. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |