Anti-phospho-SNCA (pSer129) antibody produced in rabbit
SIGMA/SAB4300139 - affinity isolated antibody
Synonym: Anti-MGC110988 antibody produced in rabbit; Anti-NACP antibody produced in rabbit; Anti-PARK1 antibody produced in rabbit; Anti-PARK4 antibody produced in rabbit; Anti-synuclein, alpha (non A4 component of amyloid precursor) antibody produced in rabbit
MDL Number: MFCD02095740
Product Type: Chemical
Immunoblotting Anti-phospho-SNCA (pSer129): SAB4300139: Analysis of extracts from mouse brain tissue using Anti-phospho-SNCA (pSer129) antibody (Lane 2) and the same antibody preincubated with blocking peptide (Lane1).
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (M-P-SP-E-E) |
| isotype | IgG |
| mol wt | ~18 kDa |
| NCBI accession no. | NP_000336.1   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, rat, human |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer129) |
| technique(s) | western blot: 1:500-1:1000 |
| UniProt accession no. | P37840 |
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| General description: | May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. |
| Immunogen: | Peptide sequence around phosphorylation site of serine 129 (M-P-S(p)-E-E), according to the protein SNCA. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |