Anti-phospho-VASP (pSer157) antibody produced in rabbit
SIGMA/SAB4300172 - affinity isolated antibody
Synonym: Anti-
Product Type: Chemical
Immunohistochemistry Anti-phospho-VASP (pSer157): SAB4300172: Analysis of paraffin-embedded human tonsil carcinoma tissue using Anti-phospho-VASP (pSer157) antibody (left) or the same antibody preincubated with blocking peptide (right).
Immunoblotting Anti-phospho-VASP (pSer157): SAB4300172: Analysis of extracts from C6 cells untreated or treated with PMA using Anti-phospho-VASP (pSer157) antibody.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (R-V-SP-N-A) |
| isotype | IgG |
| mol wt | ~50 kDa |
| NCBI accession no. | NP_003361.1   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, rat |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer157) |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P50552 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation. |
| Immunogen: | Peptide sequence around phosphorylation site of serine 157 (R-V-S(p)-N-A), according to the protein VASP. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |