Anti-phospho-NFKB1 (pSer932) antibody produced in rabbit
SIGMA/SAB4300199 - affinity isolated antibody
Synonym: Anti-DKFZp686C01211 antibody produced in rabbit; Anti-EBP-1 antibody produced in rabbit; Anti-KBF1 antibody produced in rabbit; Anti-MGC54151 antibody produced in rabbit; Anti-nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 antibody produced in rabbit
MDL Number: MFCD00802846
Product Type: Chemical
Immunohistochemistry Anti-phospho-NFKB1 (pSer932): SAB4300199: Analysis of paraffin-embedded human breast carcinoma tissue using Anti-phospho-NFKB1 (pSer932) antibody (left) or the same antibody preincubated with blocking peptide (right).
Immunoblotting Anti-phospho-NFKB1 (pSer932): SAB4300199: Analysis of extracts from 293 cells untreated or treated with TNF-α using Anti-phospho-NFKB1 (pSer932) antibody.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (E-T-SP-F-R) |
| isotype | IgG |
| mol wt | ~120 kDa |
| ~50 kDa | |
| NCBI accession no. | NP_001158884.1   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, rat, mouse |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer932) |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P19838 |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. |
| Immunogen: | Peptide sequence around phosphorylation site of serine 932 (E-T-S(p)-F-R), according to the protein NFKB1. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |