Anti-NBN (Ab-343) antibody produced in rabbit
SIGMA/SAB4300338 - affinity isolated antibody
Synonym: Anti-AT-V1 antibody produced in rabbit; Anti-AT-V2 antibody produced in rabbit; Anti-ATV antibody produced in rabbit; Anti-FLJ10155 antibody produced in rabbit; Anti-nibrin antibody produced in rabbit
Product Type: Chemical
Immunohistochemistry Anti-NBN (Ab-343): SAB4300338: Analysis of paraffin-embedded human breast carcinoma tissue using Anti-NBN (Ab-343) antibody (left) or the same antibody preincubated with blocking peptide (right).
Immunoblotting Anti-NBN (Ab-343): SAB4300338: Analysis of extracts from Jurkat cells using Anti-NBN (Ab-343) antibody and the same antibody preincubated with blocking peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (S-L-S-Q-G) |
| isotype | IgG |
| mol wt | ~95 kDa |
| NCBI accession no. | NP_002476.2   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | O60934 |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Mutations in p95/NBS1 gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. |
| Immunogen: | Peptide sequence around aa. 341-345 (S-L-S-Q-G), according to the protein NBN. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |