Anti-MYOD1 (Ab-200) antibody produced in rabbit
SIGMA/SAB4300397 - affinity isolated antibody
Synonym: Anti-MYF3 antibody produced in rabbit; Anti-MYOD antibody produced in rabbit; Anti-PUM antibody produced in rabbit; Anti-bHLHc1 antibody produced in rabbit; Anti-myogenic differentiation 1 antibody produced in rabbit
MDL Number: MFCD01323984
Product Type: Chemical
Immunoblotting Anti-MYOD1 (Ab-200): SAB4300397: Analysis of extracts from HeLa cells using Anti-MYOD1 (Ab-200) antibody and the same antibody preincubated with blocking peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (A-S-S-P-R) |
| isotype | IgG |
| mol wt | ~40 kDa |
| NCBI accession no. | NP_002469.2   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1:500-1:1000 |
| UniProt accession no. | P15172 |
| Biochem/physiol Actions: | Lack of MyoD (myogenic differentiation) results in a perinatally lethal fetal akinesia. It brings histone-modifying enzymes, which help to induce muscle differentiation. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
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| General description: | MyoD encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis. |
| General description: | MYOD1 (myogenic differentiation 1) gene codes for a nuclear protein, that is a member of the basic helix-loop-helix (bHLH) family of transcription factors and the myogenic factors subfamily. It is located on human chromosome 11p15.1. |
| Immunogen: | Peptide sequence around aa. 198!202 (A-S-S-P-R), according to the protein MYOD1. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |