Anti-PRKD1 (Ab-910) antibody produced in rabbit
SIGMA/SAB4300400 - affinity isolated antibody
Synonym: Anti-PKC-MU antibody produced in rabbit; Anti-PKCM antibody produced in rabbit; Anti-PKD antibody produced in rabbit; Anti-PRKCM antibody produced in rabbit; Anti-protein kinase D1 antibody produced in rabbit
MDL Number: MFCD03455823
Product Type: Chemical
Immunoblotting Anti-PRKD1 (Ab-910): SAB4300400: Analysis of extracts from HeLa, 293 and 3T3 cells using Anti-PRKD1 (Ab-910) antibody.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (R-V-S-I-L) |
| isotype | IgG |
| mol wt | ~115 kDa |
| NCBI accession no. | NP_002733.2   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1:500-1:1000 |
| UniProt accession no. | Q15139 |
| Biochem/physiol Actions: | PRKD1 (Protein kinase D 1) is a negative modulator of cell migration . It plays an important role in cell adhesion, cell migration, vesicle transport, cell survival , signal transduction, membrane trafficking and immune function. It preserves the epithelial phenotype by inhibiting epithelial-to-mesenchymal transition. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-kappa-B. |
| General description: | PRKD1 gene encodes PKD1 (protein kinase D1), that belongs to the protein kinase D family. It is a serine/threonine kinase, which is expressed in cells of the normal mammary gland. The PRKD1 gene promoter has a great CpG island covering 1.2kb, including the transcription start site and the entire exon 1. |
| Immunogen: | Peptide sequence around aa. 908-912 (R-V-S-I-L), according to the protein PRKD1. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |