Anti-HDAC2 (Ab-394) antibody produced in rabbit
SIGMA/SAB4300412 - affinity isolated antibody
Synonym: Anti-RPD3 antibody produced in rabbit; Anti-YAF1 antibody produced in rabbit; Anti-histone deacetylase 2 antibody produced in rabbit
MDL Number: MFCD02686596
Product Type: Chemical
Immunohistochemistry Anti-HDAC2 (Ab-394): SAB4300412: Analysis of paraffin-embedded human breast carcinoma tissue using Anti-HDAC2 (Ab-394) antibody (left) or the same antibody preincubated with blocking peptide (right).
Immunofluorescence Anti-HDAC2 (Ab-394): SAB4300412: Staining of methanol-fixed HeLa cells using Anti-HDAC2 (Ab-394) antibody (Red).
Immunoblotting Anti-HDAC2 (Ab-394): SAB4300412: Analysis of extracts from 293 and HeLa cells using Anti-HDAC2 (Ab-394) antibody.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (E-D-S-G-D) |
| isotype | IgG |
| mol wt | ~60 kDa |
| NCBI accession no. | NP_001518.2   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 |
| indirect immunofluorescence: 1:100-1:200 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | Q92769 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. |
| Immunogen: | Peptide sequence around aa. 392-396 (E-D-S-G-D), according to the protein HDAC2. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |