Anti-GRIN2B (Ab-1474) antibody produced in rabbit
SIGMA/SAB4300425 - affinity isolated antibody
Synonym: Anti-MGC142178 antibody produced in rabbit; Anti-MGC142180 antibody produced in rabbit; Anti-NMDAR2B antibody produced in rabbit; Anti-NR2B antibody produced in rabbit; Anti-glutamate receptor, ionotropic, N-methyl D-aspartate 2B antibody produced in rabbit
MDL Number: MFCD00243314
Product Type: Chemical
Immunofluorescence Anti-GRIN2B (Ab-1474): SAB4300425: Staining of methanol-fixed HeLa cells using Anti-GRIN2B (Ab-1474) antibody (Red).
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (H-V-Y-E-K) |
| isotype | IgG |
| mol wt | ~190 kDa |
| NCBI accession no. | NP_000825.2   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, rat, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect immunofluorescence: 1:100-1:200 |
| UniProt accession no. | Q13224 |
| Biochem/physiol Actions: | GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) plays an important role in the growth of neurons and is highly essential for the learning and memory. GRIN2B mutation is associated with neuropsychiatric and developmental disorders like schizophrenia, Parkinson’s disease and bipolar disorder. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) codes for N-methyl d-aspartate receptor subtype 2B (GluN2B). It belongs to the N-methyl-D-aspartate receptor (NMDAR) gene family. It is located on human chromosome 12p13.1. |
| General description: | NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. |
| Immunogen: | Peptide sequence around aa. 1472-1476 (H-V-Y-E-K), according to the protein GRIN2B. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |