Anti-YWHAZ (Ab-58) antibody produced in rabbit
SIGMA/SAB4300449 - affinity isolated antibody
Synonym: Anti-KCIP-1 antibody produced in rabbit; Anti-MGC111427 antibody produced in rabbit; Anti-MGC126532 antibody produced in rabbit; Anti-MGC138156 antibody produced in rabbit; Anti-tyrosine 3-monooxygenase / tryptophan 5-monooxygenase activation protein, zeta polypeptide antibody produced in rabbit
Product Type: Chemical
Immunohistochemistry Anti-YWHAZ (Ab-58): SAB4300449: Analysis of paraffin-embedded human breast carcinoma tissue using Anti-YWHAZ (Ab-58) antibody (left) or the same antibody preincubated with blocking peptide (right).
Immunoblotting Anti-YWHAZ (Ab-58): SAB4300449: Analysis of extracts from HepG2 , HeLa and 293 cells using Anti-YWHAZ (Ab-58) antibody.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (R-S-S-W-R) |
| isotype | IgG |
| mol wt | ~28 kDa |
| NCBI accession no. | NP_001129171.1   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P63104 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
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| General description: | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. |
| Immunogen: | Peptide sequence around aa. 56-60 (R-S-S-W-R), according to the protein YWHAZ. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |