Anti-EFNB2 (Ab-330) antibody produced in rabbit
SIGMA/SAB4300456 - affinity isolated antibody
Synonym: Anti-EPLG5 antibody produced in rabbit; Anti-HTKL antibody produced in rabbit; Anti-Htk-L antibody produced in rabbit; Anti-LERK5 antibody produced in rabbit; Anti-ephrin-B2 antibody produced in rabbit
Product Type: Chemical
Immunofluorescence Anti-EFNB2 (Ab-330): SAB4300456: Staining of methanol-fixed HeLa cells using Anti-EFNB2 (Ab-330) antibody (Red).
Immunoblotting Anti-EFNB2 (Ab-330): SAB4300456: Analysis of extracts from HT29 cells using Anti-EFNB2 (Ab-330) antibody.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (N-I-Y-Y-K) |
| isotype | IgG |
| mol wt | ~37 kDa |
| NCBI accession no. | NP_004084.1   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect immunofluorescence: 1:100-1:200 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P52799 |
| Biochem/physiol Actions: | EFNB2 (ephrin B2) regulates the development of arterial endothelial cell. It also modulates the movement and adherence of vascular smooth muscle cells and pericytes to the extending arterial endothelial cell tubes. Overexpression of EFNB2 results in low tumor stage and elevated expression of TrkA in neuroblastomas. It controls the growth of thymocyte and differentiation of peripheral T cell. It is required for interleukin-6 (IL-6) signaling. It also modulates the antiviral immune responses. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | EFNB2 (ephrin B2) is a membrane-bound molecule , that is located on human chromosome 13q33. |
| General description: | Ephrin-B2 encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a lycosylphosphatidylinosit |
| Immunogen: | Peptide sequence around aa. 328-332 (N-I-Y-Y-K), according to the protein EFNB2. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |