Anti-RAC1 (Ab-71) antibody produced in rabbit
SIGMA/SAB4300461 - affinity isolated antibody
Synonym: Anti-MGC111543 antibody produced in rabbit; Anti-MIG5 antibody produced in rabbit; Anti-TC-25 antibody produced in rabbit; Anti-p21-Rac1 antibody produced in rabbit; Anti-ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) antibody produced in rabbit
MDL Number: MFCD01322704
Product Type: Chemical
Immunofluorescence Anti-RAC1 (Ab-71): SAB4300461: Staining of methanol-fixed HeLa cells using Anti-RAC1 (Ab-71) antibody (Red).
Immunoblotting Anti-RAC1 (Ab-71): SAB4300461: Analysis of extracts from A431 cells using Anti-RAC1 (Ab-71) antibody and the same antibody preincubated with blocking peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (P-L-S-Y-P) |
| isotype | IgG |
| mol wt | ~28 kDa |
| NCBI accession no. | NP_008839.2   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect immunofluorescence: 1:100-1:200 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P63000 |
| Application: | Anti-RAC1 (Ab-71) antibody has been used in western blot analysis . |
| Biochem/physiol Actions: | RAC1 (ras-related C3 botulinum toxin substrate 1) plays a major role in cancer invasion and metastasis. It can be considered as a therapeutic target for breast cancer. It is essential for several cellular activities like phagocytosis, adhesion, migration, motility, cell proliferation and axonal growth. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | RAC1 (ras-related C3 botulinum toxin substrate 1) is a polarity related protein , that belongs to the Rho family of small guanosine triphosphatases. It is located on human chromosome 7p22. |
| General description: | Rac1 encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. |
| Immunogen: | Peptide sequence around aa. 69-73 (P-L-S-Y-P), according to the protein RAC1. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |