Anti-RAF1 (Ab-338) antibody produced in rabbit
SIGMA/SAB4300462 - affinity isolated antibody
Synonym: Anti-CRAF antibody produced in rabbit; Anti-NS5 antibody produced in rabbit; Anti-Raf-1 antibody produced in rabbit; Anti-c-Raf antibody produced in rabbit; Anti-v-raf-1 murine leukemia viral oncogene homolog 1 antibody produced in rabbit
MDL Number: MFCD01092478
Product Type: Chemical
Immunohistochemistry Anti-RAF1 (Ab-338): SAB4300462: Analysis of paraffin-embedded human breast carcinoma tissue using Anti-RAF1 (Ab-338) antibody (left) or the same antibody preincubated with blocking peptide (right).
Immunoblotting Anti-RAF1 (Ab-338): SAB4300462: Analysis of extracts from 293 cells using Anti-RAF1 (Ab-338) antibody and the same antibody preincubated with blocking peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (R-D-S-S-Y) |
| isotype | IgG |
| mol wt | ~73 kDa |
| NCBI accession no. | NP_002871.1   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P04049 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
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| General description: | Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3. |
| Immunogen: | Peptide sequence around aa. 336-340 (R-D-S-S-Y), according to the protein RAF1. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |