Anti-IRS1 (Ab-639) antibody produced in rabbit
SIGMA/SAB4300483 - affinity isolated antibody
Synonym: Anti-HIRS-1 antibody produced in rabbit; Anti-insulin receptor substrate 1 antibody produced in rabbit
Product Type: Chemical
Immunofluorescence Anti-IRS1 (Ab-639): SAB4300483: Staining of methanol-fixed HeLa cells using Anti-IRS1 (Ab-639) antibody (Red).
Immunoblotting Anti-IRS1 (Ab-639): SAB4300483: Analysis of extracts from HT29 and 3T3 cells using Anti-IRS1 (Ab-639) antibody.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (P-K-S-V-S) |
| isotype | IgG |
| mol wt | ~180 kDa |
| NCBI accession no. | NP_005535.1   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect immunofluorescence: 1:100-1:200 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P35568 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit. |
| Immunogen: | Peptide sequence around aa. 637-641 (P-K-S-V-S), according to the protein IRS1. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |