Anti-NFKB1 (Ab-927) antibody produced in rabbit
SIGMA/SAB4300554 - affinity isolated antibody
Synonym: Anti-DKFZp686C01211 antibody produced in rabbit; Anti-EBP-1 antibody produced in rabbit; Anti-KBF1 antibody produced in rabbit; Anti-MGC54151 antibody produced in rabbit; Anti-nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 antibody produced in rabbit
MDL Number: MFCD00802846
Product Type: Chemical
Immunofluorescence Anti-NFKB1 (Ab-927): SAB4300554: Staining of methanol-fixed HeLa cells using Anti-NFKB1 (Ab-927) antibody (Red).
Immunoblotting Anti-NFKB1 (Ab-927): SAB4300554: Analysis of extracts from HeLa cells using Anti-NFKB1 (Ab-927) antibody and the same antibody preincubated with blocking peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (C-D-S-G-V) |
| isotype | IgG |
| mol wt | ~120 kDa |
| ~50 kDa | |
| NCBI accession no. | NP_001158884.1   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, rat, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect immunofluorescence: 1:100-1:200 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P19838 |
| Biochem/physiol Actions: | NFKB1 (nuclear factor κB subunit 1) controls the maturation of NK (natural killer) cells and effector functions. It helps in the upregulation of intrauterine adhesion inflammatory factors, hence it plays a major role in inflammatory diseases. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. |
| General description: | NFKB1(nuclear factor κB subunit 1) is a dimeric transcription factor. It belongs to the REL family. It is located on chromosome 4q24. |
| Immunogen: | Peptide sequence around aa. 925-929 (C-D-S-G-V ), according to the protein NFKB1. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |