Anti-OPRM1 (Ab-375) antibody produced in rabbit
SIGMA/SAB4300555 - affinity isolated antibody
Synonym: Anti-KIAA0403 antibody produced in rabbit; Anti-MOR antibody produced in rabbit; Anti-MOR1 antibody produced in rabbit; Anti-OPRM antibody produced in rabbit; Anti-opioid receptor, mu 1 antibody produced in rabbit
Product Type: Chemical
Immunoblotting Anti-OPRM1 (Ab-375): SAB4300555: Analysis of extracts from PC12 cells using Anti-OPRM1 (Ab-375) antibody and the same antibody preincubated with blocking peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (H-P-S-T-A) |
| isotype | IgG |
| mol wt | ~80 kDa |
| NCBI accession no. | NP_000905.3   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1:500-1:1000 |
| UniProt accession no. | P42866 |
| Application: | Anti-OPRM1 (Ab-375) antibody produced in rabbit has been used in Western blotting. |
| Biochem/physiol Actions: | The gene OPRM1 (opioid receptor μ 1) encodes a μ opioid receptor that functions in pain perception and addiction to drugs of abuse, such as cocaine, nicotine and alcohol. It serves as a target for opioid drugs, such as morphine, methadone and heroin and opioid peptides (like β - endorphin and endomorphins) and mediates their effects. Single nucleotide polymorphism in the OPRM1 gene is associated with an inclination to drug addiction and lesser response to painful stimuli. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for beta-endorphin. |
| General description: | The gene OPRM1 (opioid receptor μ 1) is mapped to human chromosome 6q24-q25. The gene spans a length of 200kb and contains 11 exons that yield 17 splice variants. |
| Immunogen: | Peptide sequence around aa. 373-377 (H-P-S-T-A), according to the protein OPRM1. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |