Anti-SMAD1 (Ab-465) antibody produced in rabbit
SIGMA/SAB4300561 - affinity isolated antibody
Synonym: Anti-BSP1 antibody produced in rabbit; Anti-JV4-1 antibody produced in rabbit; Anti-JV41 antibody produced in rabbit; Anti-MADH1 antibody produced in rabbit; Anti-SMAD family member 1 antibody produced in rabbit
Product Type: Chemical
Immunofluorescence Anti-SMAD1 (Ab-465): SAB4300561: Staining of methanol-fixed HeLa cells using Anti-SMAD1 (Ab-465) antibody (Red).
Immunoblotting Anti-SMAD1 (Ab-465): SAB4300561: Analysis of extracts from HeLa cells using Anti-SMAD1 (Ab-465) antibody.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (I-S-S-V-S) |
| isotype | IgG |
| mol wt | ~55 kDa |
| NCBI accession no. | NP_001003688.1   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect immunofluorescence: 1:100-1:200 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | Q15797 |
| Biochem/physiol Actions: | SMAD1 (SMAD family member 1) protein has a major role in disease development, hence it acts as a biologic prognostic factor in diseases. The miR-345 repress the multiplication, invasion and migration of prostate cancer by downregulating Smad1. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Smad1 (SMAD family member 1) is a transcriptional activator, that is located on chromosome 4q31. |
| General description: | Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). |
| Immunogen: | Peptide sequence around aa. 461-465 (I-S-S-V-S), according to the protein SMAD1. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |