Anti-STAT2 (Ab-690) antibody produced in rabbit
SIGMA/SAB4300591 - affinity isolated antibody
Synonym: Anti-ISGF-3 antibody produced in rabbit; Anti-MGC59816 antibody produced in rabbit; Anti-P113 antibody produced in rabbit; Anti-STAT113 antibody produced in rabbit; Anti-signal transducer and activator of transcription 2, 113kDa antibody produced in rabbit
Product Type: Chemical
Immunohistochemistry Anti-STAT2 (Ab-690): SAB4300591: Analysis of paraffin-embedded human lung carcinoma tissue using Anti-STAT2 (Ab-690) antibody (left) or the same antibody preincubated with blocking peptide (right).
Immunoblotting Anti-STAT2 (Ab-690): SAB4300591: Analysis of extracts from HeLa cells using Anti-STAT2 (Ab-690) antibody and the same antibody preincubated with blocking peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (R-K-Y-L-K) |
| isotype | IgG |
| mol wt | ~113 kDa |
| NCBI accession no. | NP_005410.1   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P52630 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | STAT2 encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. |
| Immunogen: | Peptide sequence around aa. 688-692 (R-K-Y-L-K), according to the protein STAT2. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |