Anti-FLT4 antibody produced in rabbit
SIGMA/SAB4300609 - affinity isolated antibody
Synonym: Anti-FLT41 antibody produced in rabbit; Anti-LMPH1A antibody produced in rabbit; Anti-PCL antibody produced in rabbit; Anti-VEGFR3 antibody produced in rabbit; Anti-fms-related tyrosine kinase 4 antibody produced in rabbit
MDL Number: MFCD03097363
Product Type: Chemical
Immunoblotting Anti-FLT4: SAB4300609: Analysis of extracts from HUVEC cells using Anti-FLT4and the same antibody preincubated with blocking peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (L-A-S-E-E) |
| isotype | IgG |
| mol wt | ~160 kDa |
| NCBI accession no. | NP_002011.2   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1:500-1:1000 |
| UniProt accession no. | P35916 |
| Application: | Anti-FLT4 antibody produced in rabbit has been used in immunohistochemistry. |
| Biochem/physiol Actions: | Fms related tyrosine kinase 4 (FLT4) has a role in lymphangiogenesis and angiogenesis. It acts as an activator in signaling pathways. Mutations in the gene encoding FLT4 have been linked to Milroy disease. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
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| General description: | Fms related tyrosine kinase 4 (FLT4) is also known as vascular endothelial growth factor receptor 3 (VEGFR3). It is expressed in the blood and lymphatic endothelial cells during early development. The gene encoding FLT4 is localized on human chromosome 5q35.3. |
| General description: | Receptor for VEGFC. Has a tyrosine-protein kinase activity. |
| Immunogen: | Peptide sequence around aa. 1279-1283 (L-A-S-E-E), according to the protein FLT4. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |