Anti-FGFR4 antibody produced in rabbit
SIGMA/SAB4300637 - affinity isolated antibody
Synonym: Anti-CD334; Anti-JTK2; Anti-MGC20292; Anti-TKF
Product Type: Chemical
Immunoblotting Anti-FGFR4 Cat. No. SAB4300637: Analysis of extract from rat liver and rat brain tissue using Anti-FGFR4 antibody.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (L-T-V-A-L) |
| isotype | IgG |
| mol wt | ~110 kDa |
| NCBI accession no. | NM_002011.3   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1:500-1:1000 |
| UniProt accession no. | P22455 |
| Biochem/physiol Actions: | Aberrations in FGFR4 results in neuroblastoma and altered receptor degradation. It acts as a predictive biomarker in oral and oropharyngeal squamous cell carcinoma. Suppressing FGFR4 may affect the biological characteristics in gastric cancer cells. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | FGFR4 (fibroblast growth factor receptor 4) belongs to FGFR kinase family. In adult tissues, FGFR is expressed in a cell type-specific mode. It is located on chromosome 5q35. The antibody detects endogenous level of total FGFR4 protein. |
| General description: | Receptor for acidic fibroblast growth factor. Does not bind to basic fibroblast growth factor. Binds FGF19. |
| Immunogen: | Peptide sequence around aa. 45-49 ( L-T-V-A-L), according to the protein NP_002002.3 |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |