Anti-ABL1/2 (Ab-393/429) antibody produced in rabbit
SIGMA/SAB4300641 - affinity isolated antibody
Synonym: Anti-ABL; Anti-JTK7; Anti-c-ABL; Anti-p150; Anti-v-abl
Product Type: Chemical
Immunoblotting Anti-ABL1/2 (Ab-393/429) Cat. No. SAB4300641: Analysis of extract from MCF-7, 293, HepG2 cells using Anti-ABL1/2 (Ab-393/429) antibody.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (D-T-Y-T-A) |
| isotype | IgG |
| mol wt | 135-210 kDa |
| NCBI accession no. | NM_001136000.2   |
| NM_005157.3 |
|
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1:500-1:1000 |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks. |
| General description: | The antibody detects endogenous levels of total ABL1/2 protein. |
| Immunogen: | Peptide sequence around aa. 391-395 (D-T-Y-T-A), according to the protein NP_005148.2, NP_001129472.1 |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |