Anti-Vimentin antibody produced in rabbit
SIGMA/SAB4300676 - affinity isolated antibody
Synonym: Anti-FLJ36605; Anti-VIM
Product Type: Chemical
Immunoblotting Anti-Vimentin Cat. No. SAB4300676: Analysis of extract from HeLa, cos7 and JK cells using Anti-Vimentin antibody.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (G-Q-V-I-N) |
| isotype | IgG |
| mol wt | ~57 kDa |
| NCBI accession no. | NM_003380.3   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | monkey, mouse, human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1:500-1:1000 |
| Biochem/physiol Actions: | Vimentin helps to preserve the structure of cell and stability of tissue in mesenchymal cells. It is involved in tumorigenesis, EMT (epithelial mesenchymal transition) and the metastatic spread of cancer. It also controls infectious internalization of human papillomavirus 16 pseudovirions. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Vimentin is a specific type III intermediate filament (IF) protein. It is abundantly expressed in mesenchymal cells. It is located on human chromosome 10p13. The antibody detects endogenous level of total Vimentin protein. |
| General description: | Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. |
| Immunogen: | Peptide sequence around aa. 452-456 (G-Q-V-I-N), according to the protein NP_003371.2 |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |