Anti-phospho-Cyclin E1 (pThr395) antibody produced in rabbit
SIGMA/SAB4300684 - affinity isolated antibody
Synonym: Anti-CCNE; Anti-CCNE1
Product Type: Chemical
Immunoblotting Anti-phospho-Cyclin E1 (pThr395) Cat. No. SAB4300684: Analysis of extracts from 293 cells untreated or treated with hydroxyurea using Anti-phospho-Cyclin E1 (pThr395) antibody.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (L-L-Tp-P-P) |
| isotype | IgG |
| mol wt | ~48 kDa |
| NCBI accession no. | NM_001238.1   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pThr395) |
| technique(s) | western blot: 1:500-1:1000 |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | The antibody detects endogenous level of Cyclin E1 only when phosphorylated at threonine 395. |
| General description: | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. |
| Immunogen: | Peptide sequence around phosphorylation site of threonine 395 (L-L-Tp-P-P), according to the protein NP_001229.1 |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |