Anti-phospho-DRP1 (pSer637) antibody produced in rabbit
SIGMA/SAB4301399 - affinity isolated antibody
Synonym: DLP1; DNM1L; DRP1; DVLP; Dymple
Product Type: Product-on-demand
Immunoblotting Anti-phospho-DRP1 (pSer637): Cat. No. SAB4301399: Western blot analysis of extracts from JK cells and K562 cells using Anti-phospho-DRP1 (pSer637) antibody.
| accession no. | NP_036192.2. |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1.0 mg/mL |
| form | buffered aqueous solution |
| isotype | IgG |
| mol wt | 82 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer637) |
| technique(s) | western blot: 1:500-1:1000 (Cell Lysate) |
| UniProt accession no. | O00429  |
| Application: | Anti-phospho-DRP1 (pSer637) antibody produced in rabbit has been used in immunoblotting and western blotting. |
| Biochem/physiol Actions: | Dynamin related protein 1 (DRP1) is an important regulator of mitochondrial fission and peroxisomal division. It regulates proper mitochondrial function, apoptosis and necrosis. Mutations in this gene is associated with Alzheimer′s disease. |
| Biochem/physiol Actions: | The antibody detects endogenous levels of DRP1 only when phosphorylated at serine 637. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Dynamin related protein 1 (DRP1) is a dynamin-related guanosine triphosphatase. The gene is located on human chromosome 12p11.21. DRP1 is a cytosolic protein, which is also present on the outer mitochondrial membrane. |
| Immunogen: | Peptide sequence around phosphorylation site of Serine637(K-L-S(p)-A-R) derived from Human DRP1. |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |