Anti-Cofilin antibody produced in rabbit
SIGMA/SAB4500148 - affinity isolated antibody
Synonym: CFL; CFL1; CFL2; Cofilin 2; Cofilin-1
MDL Number: MFCD03791485
Product Type: Chemical
Western Blotting Anti-Cofilin: Cat. No. SAB4500148: Immunoblotting analysis of extracts from Jurkat/HeLa cells, using Anti-Cofilin antibody. The lane on the left was treated with the Anti-Cofilin antibody. The lane on the right (negative control) was treated with both Anti-Cofilin antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 18 kDa |
| NCBI accession no. | Q9Y281   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:40000 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P23528 |
| Application: | Anti-Cofilin antibody has been used in western blotting. |
| Biochem/physiol Actions: | Cofilin plays an important role in actin filament remodeling that is required in chemotaxis, cell migration and invasion of tumor cells. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-Cofilin Antibody detects endogenous levels of total Cofilin protein. |
| General description: | Cofilin is a member of the actin depolymerizing factor/cofilin family. Among all members, cofilin‐1 is the predominant isoform. It is located on human chromosome 11q13. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Cofilin. Immunogen Range: 61-110 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |