Anti-PARK7 antibody produced in rabbit
SIGMA/SAB4500249 - affinity isolated antibody
Synonym: Oncogene DJ1; Parkinson disease protein 7; Protein DJ-1
Product Type: Chemical
Western Blotting Anti-PARK7: Cat. No. SAB4500249: Immunoblotting analysis of extracts from HuvEc/JurKat/HeLa/COLO205/293 cells, using Anti-PARK7 antibody. The lane on the left was treated with the Anti-PARK7 antibody. The lane on the right (negative control) was treated with both Anti-PARK7 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 19 kDa |
| NCBI accession no. | Q99497   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:20000 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | Q99497 |
| Application: | Anti-PARK7 antibody produced in rabbit is suitable for indirect ELISA and western blot applications. |
| Biochem/physiol Actions: | PARK7 is a member of novel glyoxalase family. It exerts mitochondrial activity. It has been suggested that PARK7 may act as an antioxidant and/or a molecular chaperone. It may also detoxify aggressive metabolic aldehyde by-products. It helps in stabilizing mitochondria during cellular stress. Alteration in gene function affects neurodegeneration, which leads to the autosomal recessive early-onset parkinsonism. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-PARK7 Antibody detects endogenous levels of total PARK7 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human PARK7. Immunogen Range: 61-110 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |