Anti-TSH2 antibody produced in rabbit
SIGMA/SAB4500379 - affinity isolated antibody
Synonym: OVC10-2; Ovarian cancer-related protein 10-2; Zinc finger protein 218
Product Type: Chemical
Immunohistochemistry Anti-TSH2: Cat. No. SAB4500379: Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue using Anti-TSH2 antibody. Cells on the left were treated with the Anti-TSH2 antibody. Cells on the right (negative control) were treated with both Anti-TSH2 antibody and the synthesized immunogen peptide.
Immunofluorescence Anti-TSH2: Cat. No. SAB4500379: Immunofluorescence of MCF7 cells using Anti-TSH2 antibody. Cells on the left were treated with the Anti-TSH2 antibody. Cells on the right (negative control) were treated with both Anti-TSH2 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 115 kDa |
| NCBI accession no. | Q9NRE2   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:20000 |
| immunofluorescence: 1:100-1:500 | |
| immunohistochemistry: 1:50-1:100 | |
| UniProt accession no. | Q9NRE2 |
| Biochem/physiol Actions: | TSH2/TSHZ2 (teashirt zinc finger homeobox 2) acts as a C-terminal binding protein (CtBP)-dependent transcriptional repressor. At the time of mammary tumorigenesis, low level expression of TSH2 liberates GLI1 (glioma-associated oncogene homolog 1) from the nuclear repressor complex to update its transcriptional activity. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-TSH2 Antibody detects endogenous levels of total TSH2 protein. |
| General description: | TSH2/TSHZ2 (teashirt zinc finger homeobox 2) is a nuclear protein. It has four zinc-finger (ZF) domains, a homeobox domain and a coiled-coil domain. It is located on human chromosome 20q13.2. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human TSH2. Immunogen Range: 811-860 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |