Anti-Collagen XII α1 antibody produced in rabbit
SIGMA/SAB4500395 - affinity isolated antibody
Synonym: COCA1; Collagen α-1(XII) chain
Product Type: Chemical
Immunohistochemistry Anti-Collagen XII α1: Cat. No. SAB4500395: Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue using Anti-Collagen XII α1 antibody. Cells on the left were treated with the Anti-Collagen XII α1 antibody. Cells on the right (negative control) were treated with both Anti-Collagen XII α1 antibody and the synthesized immunogen peptide.
Immunofluorescence Anti-Collagen XII α1: Cat. No. SAB4500395: Immunofluorescence of COS7 cells using Anti-Collagen XII α1 antibody. Cells on the left were treated with the Anti-Collagen XII α1 antibody. Cells on the right (negative control) were treated with both Anti-Collagen XII α1 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 333 kDa |
| NCBI accession no. | Q99715   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:1000 |
| immunofluorescence: 1:100-1:500 | |
| immunohistochemistry: 1:50-1:100 | |
| UniProt accession no. | Q99715 |
| Application: | Anti-Collagen XII α1 antibody has been used in immunohistochemistry. |
| Biochem/physiol Actions: | Collagen XII α1 participates in a benign bone tumor, subungual exostosis. Collagen XII organize the collagen fibrils and thereby preserves the bone and muscle integrity. Mutations in collagen XII results in Ehlers–Danlos/myopathy overlap syndrome. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-Collagen XII α1 Antibody detects endogenous levels of total Collagen XII α1 protein. |
| General description: | Collagen XII α1 belongs to the FACIT collagens (fibril-associated collagens with interrupted triple helices) family. It codes for the alpha chain of type XII collagen. It is located on human chromosome 6q13. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Collagen XII alpha1. Immunogen Range: 1481-1530 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |