Anti-GPR151 antibody produced in rabbit
SIGMA/SAB4500418 - affinity isolated antibody
Synonym: G-protein coupled receptor PGR7; GPCR-2037; GPR151; PGR7; Probable G-protein coupled receptor 151
Product Type: Chemical
Immunofluorescence Anti-GPR151: Cat. No. SAB4500418: Immunofluorescence of HuvEc cells using Anti-GPR151 antibody. Cells on the left were treated with the Anti-GPR151 antibody. Cells on the right (negative control) were treated with both Anti-GPR151 antibody and the synthesized immunogen peptide.
Western Blotting Anti-GPR151: Cat. No. SAB4500418: Immunoblotting analysis of extracts from K562 cells, using Anti-GPR151 antibody. The lane on the left was treated with the Anti-GPR151 antibody. The lane on the right (negative control) was treated with both Anti-GPR151 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 46 kDa |
| NCBI accession no. | Q8TDV0   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:1000 |
| immunofluorescence: 1:100-1:500 | |
| western blot: 1:500-1:1000 |
| Application: | Anti-GPR151, C-Terminal antibody produced in rabbit has been used for Western blotting. |
| Biochem/physiol Actions: | G protein-coupled receptor 151 (GPR151) is a highly conserved protein, and acts as a potential target for psychiatric drug development, due to its expression in habenular neurons which may be critically involved in the pathophysiology of psychiatric disorders such as addiction and depression. Experimental studies reveal that GPR151 might play a neuroprotective and/or pro-regenerative role in the dorsal root ganglion (DRG) after nerve injury. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | G protein-coupled receptor 151 (GPR151) is encoded by the gene mapped to human chromosome 5. It belongs to the A type of G protein-coupled receptor (GPCR) family and it shows homology with galanin receptor 2 and 3. In mice, GPR151 transcript is highly and specifically expressed in habenular neurons. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human GPR151. Immunogen Range: 370-419 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |