Anti-CRABP2 antibody produced in rabbit
SIGMA/SAB4500440 - affinity isolated antibody
Synonym: CRABP-II; Cellular retinoic acid-binding protein 2; Cellular retinoic acid-binding protein II; Retinoic acid-binding protein II; cellular
Product Type: Chemical
Western Blotting Anti-CRABP2: Cat. No. SAB4500440: Immunoblotting analysis of extracts from HT-29 cells, using Anti-CRABP2 antibody. The lane on the left was treated with the Anti-CRABP2 antibody. The lane on the right (negative control) was treated with both Anti-CRABP2 antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 15 kDa |
| NCBI accession no. | P29373   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:20000 |
| western blot: 1:500-1:1000 |
| Application: | Anti-CRABP2 antibody produced in rabbit is suitable for indirect ELISA and western blot analysis. |
| Biochem/physiol Actions: | Cellular retinoic acid binding protein 2 (CRABP2) plays a crucial role in acceleration of the transcriptional activity. In the nucleus, by binding directly to the nuclear receptor RAR, it forms a complex for connecting retinoic acid (RA) from the binding protein to the receptor. This interaction finally helps to accelerate the transcriptional activity. It may have impact in the immature phenotype in glioma cells. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Anti-CRABP2 Antibody detects endogenous levels of total CRABP2 protein. |
| General description: | Cellular retinoic acid binding protein 2 (CRABP2) is an intracellular lipid-binding protein, involved in the stimulation of receptor transcriptional activity. It has been reported that CRABP-II contains three potential sUMOylation sites centered at K45, K87, and K102. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CRABP2. Immunogen Range: 41-90 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |