Anti-Adrenergic Receptor α-2A antibody produced in rabbit
SIGMA/SAB4500548 - affinity isolated antibody
Synonym: α-2 adrenergic receptor subtype C10; α-2A adrenergic receptor; α-2A adrenoceptor; α-2A adrenoreceptor; α-2AAR
MDL Number: MFCD01321639
Product Type: Chemical
Immunohistochemistry Anti-Adrenergic Receptor α-2A: Cat. No. SAB4500548: Immunohistochemistry analysis of paraffin-embedded human testis tissue using Anti-Adrenergic Receptor α-2A antibody. Cells on the left were treated with the Anti-Adrenergic Receptor α-2A antibody. Cells on the right (negative control) were treated with both Anti-Adrenergic Receptor α-2A antibody and the synthesized immunogen peptide.
Immunofluorescence Anti-Adrenergic Receptor α-2A: Cat. No. SAB4500548: Immunofluorescence of NIH-3T3 cells using Anti-Adrenergic Receptor α-2A antibody. Cells on the left were treated with the Anti-Adrenergic Receptor α-2A antibody. Cells on the right (negative control) were treated with both Anti-Adrenergic Receptor α-2A antibody and the synthesized immunogen peptide.
Western Blotting Anti-Adrenergic Receptor α-2A: Cat. No. SAB4500548: Immunoblotting analysis of extracts from Jurkat/LOVO cells, using Anti-Adrenergic Receptor α-2A antibody. The lane on the left was treated with the Anti-Adrenergic Receptor α-2A antibody. The lane on the right (negative control) was treated with both Anti-Adrenergic Receptor α-2A antibody and the synthesized immunogen peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 48 kDa |
| NCBI accession no. | P08913   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: 1:20000 |
| immunofluorescence: 1:100-1:500 | |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P08913 |
| Biochem/physiol Actions: | ADRA2A (α-2A adrenergic receptor gene) plays an important role in irritability, impulsivity, aggression and memory traits. Mutations in ADRA2A affects the liberation of insulin and glucose regulation. Variations in ADRA2A is linked with poor clinical prognostication. It participates in autism spectrum disorders (ASDs). |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
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| General description: | ADRA2A (α-2A adrenergic receptor gene) is located on human chromosome 10q25. It is expressed in the caudate nucleus. |
| General description: | Anti-Adrenergic Receptor α-2A Antibody detects endogenous levels of total Adrenergic Receptor α-2A protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Adrenergic Receptor alpha-2A. Immunogen Range: 331-380 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |